A large spider from the jungles of South America is accidentally transported in a crate with a dead body to America where it mates with a local spider. Soon after, the residents of a small California town disappear as the result of spider bites from the deadly spider offspring. It's up to a couple of doctors with the help of an insect exterminator to annihilate these eight legged freaks.
Pete Sandich is a reckless fire-fighting pilot who is killed in what was to have been his final mission. Ascending to Heaven, Pete is introduced to business-like angel who instructs the spectral Pete to pass on his aviation knowledge to his young successor. While doing so, Pete also smoothes the course of romance for his earthly girlfriend who, after several months of grieving, finally falls in love with another man.
Una specie di ragni molto velenosi, importata erroneamente dal Venezuela, prolificherà molto rapidamente e si insinuerà in una tranquilla casa di provincia. Gli inquilini, insieme a tutta la cittadina, sono ignari di ciò che li aspetta...